University of Ottawa NMR Facility Web Site

Please feel free to make suggestions for future posts by emailing Glenn Facey.



Friday, September 12, 2008

Baseline Correction in 2D NMR Spectra

Sometimes a 1D NMR spectrum will have a baseline roll. One way of correcting this is to fit the baseline of the spectrum (between two limits) to a polynomial and then subtract the polynomial from the spectrum to produce a flat baseline. Baseline roll is not an exclusive problem to 1D data. It can also be present in each domain of a 2D data set. Baseline orrection can be applied to each of the dimensions. The figure below shows a proton NOESY spectrum which is uncorrected (top left), baseline corrected in the rows (top right), baseline corrected in the columns (bottom left) and baseline corrected in both domains (bottom right).

No comments: