Wednesday, October 24, 2007
Measurement of 13C-19F Coupling in a 1H-13C HMBC
It is often difficult to find the 13C signals in fluorinated organics by direct 13C observation. It may sometimes be easier to find these signals by way of a 1H-13C HMBC spectrum if there are nearby protons in the molecule. As shown below, it is even possible to measure the 13C-19F coupling constants.