University of Ottawa NMR Facility Web Site

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Tuesday, August 28, 2007

NMR Chromatography

The DOSY (Diffusion Ordered Spectroscopy) experiment can be used to resolve the components of a mixture. The technique uses pulsed magnetic field gradients to resolve mixtures based on the different diffusion constants of the components of the mixture. The figure shows the resolution of a mixture of small molecules. The proton spectrum of the mixture is in the horizontal domain and the diffusion constants are in the vertical dimension.



2 comments:

Anonymous said...

Where does the special DOSY processing software (such as the DOSY plugin, Mnova, etc) offer much advantage over the bruker built-in software?

Thanks.

Glenn Facey said...

Anonymous,

Thank you for your question. I have never used the plugin for the Mnova software, so I cannot comment on it. I would suggest getting in touch with the good people at Mnova.

Glenn